Histological ageing of fractures in infants: A practical algorithm for assessing infants suspected of accidental or non-accidental injury
Histopathology May 04, 2019
Naqvi A, et al. - In this investigation, researchers, for the first time, systematically documented histological characteristics of fractures of known age in infants (≦12 months). They conducted this investigation to provide histopathologists examining fractures from cases of accidental or non-accidental injury with a practical tool to age traumatic injuries of bones. From 52 anonymised infants over a period of 32 years, 169 fractures of known age at death were obtained. The data presented here show that all fractures seem to go through similar linear patterns of histological changes, with biological variation affecting differences in individual healing rates. Because it is not possible to know where fractures might lie within the biological spectrum, it is not possible to age precisely, but the data show that a time span during which the fracture occurred can be given with a high degree of certainty. This paper describes the final 2017 audit data set. The investigation was terminated at the end of 2016, as for three consecutive audits there were no material changes in the data set.
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