Ronen S, Suster D, Chen WS, et al. - The study was conducted to explore the histologic patterns of cutaneous metastases of breast carcinoma. Researchers examined 232 cases of breast carcinoma with cutaneous metastases from 2 large institutions. They compared all cases of carcinoma of the breast with involvement of the skin of the anterior chest wall with those with distant cutaneous metastases. They enrolled 232 cases in 199 patients, of which 126 had skin involvement exclusively involving the ipsilateral anterior chest, and 106 had biopsy-proven distant cutaneous metastases. As per the results, a comparison of the clinicopathologic features of the patients implies that alternate biological mechanisms may apply for local and distant skin metastases from breast carcinoma.