Hebert AA, Bobonich MA, Capriles CR, et al. - In pediatric patients with psoriasis, greater skin clearance and scalp resolution were found to be related to better patient-reported outcomes over a short-term (12-week) and long-term (48-week) span. This implies that in this population, greater improvement of skin clearance and scalp resolution could benefit quality of life.

• Data were obtained from the IXORA-PEDS trial, to assess improvement in psoriasis clearance in challenging body areas in pediatric patients relative to health-related quality of life.

• Significant association was found between higher rates of Dermatology Life Quality Index (DLQI)/Children's DLQI (CDLQI) (0,1) scores and greater Psoriasis Area and Severity Index and Psoriasis Scalp Severity Index responses at both Week 12 and Week 48.

• A significant relation also existed between DLQI/CDLQI (0,1) and static Physicians' Global Assessment of psoriasis scores.

• In those exhibiting greater levels of palmoplantar clearance, as measured by Palmoplantar Psoriasis Area and Severity Index at Week 12, there were significantly higher rates of DLQI/CDLQI (0,1) scores, however, significance was not sustained at Week 48.