Higher prevalence of metabolic disorders in patients with bilateral primary aldosteronism than unilateral primary aldosteronism
Clinical Endocrinology Aug 25, 2020
Zhang Z, Luo Q, Tuersun T, et al. - In this retrospective cross‐section study, researchers sought to examine the prevalence of metabolic syndrome (MetS) and its components in the two major types of patients with adrenal venous sampling (AVS)‐confirmed unilateral primary aldosteronism (PA) and bilateral PA. They examined metabolic parameters from 169 PA patients subtyped by AVS, involving 85 unilateral PA patients and 84 bilateral PA patients, and also involved 169 non‐PA patients matched for age and gender. According to findings, patients with bilateral PA have a higher prevalence of MetS than patients with unilateral PA, despite unilateral PA patients showing higher concentrations of aldosterone and lower serum potassium, indicating that unilateral PA and bilateral PA may have different MetS mechanisms.
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