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High trophinin-associated protein expression is an independent predictor of poor survival in liver cancer

Digestive Diseases and Sciences Oct 09, 2018

Jiao Y, et al. - Based on an analysis of The Cancer Genome Atlas Liver Hepatocellular Carcinoma (TCGA-LIHC) data, researchers assessed the association of trophinin-associated protein (TROAP) expression in hepatocellular carcinoma (HCC) tissue with clinicopathologic parameters and survival time in patients with liver cancer. By Chi-square tests, associations between TROAP expression in HCC tissues and clinical parameters were estimated. Findings suggested an association of survival status, T stage, clinical stage, and gender with high TROAP expression. Compared with 5.80 years for patients with low TROAP-expressing liver cancers, patients with high TROAP-expressing liver cancers had a shorter median overall survival of 3.83 years. The present data indicated that poor survival in liver cancer is independently predicted by TROAP expression.

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