Davis WT, et al. - Adults presenting to a community emergency department (ED) with neck or back pain were investigated for clinical characteristics associated with pyogenic spinal infection as well as for the frequency of these characteristics among patients with spinal epidural abscess (SEA). In this prospective cohort study of adults with neck or back pain, phase 1 (Jan 2004–Mar 2010) included patients with and without pyogenic spinal infection and phase 2 (Apr 2010–Aug 2018) included only patients with pyogenic spinal infection. Among the 223 patients analyzed, pyogenic spinal infection was reported in 89. Pyogenic spinal infection was noted to be correlated to male sex, fever, and recent soft tissue infection or bacteremia.