Golub SA, Rachel FA, Starbuck L, et al. - Researchers conducted a national online survey in the United States among 1,808 transmasculine individuals who were 18-60 years of age (30% people of color and/or Latinx), concerning sexual behavior and sexual healthcare, including preexposure prophylaxis (PrEP), to determine the number of individuals eligible for PrEP and the predictors of PrEP eligibility among these individuals. One or more criterion for PrEP eligibility was met by a considerable percentage of transmasculine individuals (n = 439; 24.3%) but satisfactory PrEP services were received by only a few of them. They noted lower PrEP eligibility among heterosexual-identified and higher-income patients; higher PrEP eligibility was seen among participants who were in open relationships and reported substance use. PrEP-eligible individuals who had a binary gender identity, identified as gay, and were taking testosterone reported receipt of a PrEP prescription more frequently. Findings emphasize improving efforts by providers, programs, and systems to estimate HIV-related risk in transmasculine patients and involve them in comprehensive sexual healthcare.