Yang L, et al. - Investigators assessed 6847 head and neck squamous cell carcinoma (HNSCC) cases to quantify the predictive influence of peripheral blood neutrophil-to-lymphocyte ratio (NLR) and the platelet-to-lymphocyte ratio (PLR) on survival prognosis in subjects with HNSCC. They observed that high pretreatment NLR predicted poor overall survival, disease-free survival, progression-free survival, and cancer-specific survival in HNSCC but no significant link was noted between PLR and overall survival or disease-free survival.