Feng R, et al. - With the aid of third-generation dual-source computed tomographic (CT), the feasibility, image quality, and radiation dose of prospectively high-pitch coronary CT angiography in patients with sinus rhythm and heart rates (HRs) between 70 and 100 beats per minute were determined. No statistical variations in objective parameters and subjective assessment of image quality were noted. Among subjects with high HR and without cardiac arrhythmia, images with comparatively high diagnostic ratio and considerably lower radiation dose could be obtained via prospectively high-pitch spiral acquisition using third-generation dual-source CT at systolic phase compared with prospectively sequential acquisition mode.