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High interlaboratory and interobserver agreement of somatostatin receptor immunohistochemical determination and correlation with response to somatostatin analogs

Human Pathology Nov 30, 2017

Kasajima A, et al. - The authors undertook an exploratory study of the high interlaboratory and interobserver agreement of somatostatin receptor immunohistochemical analysis in patients with neuroendocrine neoplasms. The results illustrated a positive link with clinical efficacy to somatostatin analogs, as well as simple and widespread use. Hence, HER2-Score could serve as a standard evaluation procedure of somatostatin receptors 2A (SSTR2A) and 5 (SSTR5) expression in neuroendocrine neoplasms.
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