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High incidence of autoimmune gastritis in patients misdiagnosed with two or more failures of H. pylori eradication

Alimentary Pharmacology and Therapeutics Jul 18, 2018

Furuta T, et al. - The incidence of autoimmune gastritis (AIG) in consecutive patients who consulted the department for H. pylori eradication with reference to eradication history was examined in this analysis. From June 2015 to June 2017, 404 consecutive patients who visited the H. pylori-specific out-patient unit of the hospital were recruited. Results revealed that urease-positive bacteria, like Klebsiella pneumoniae and alpha-streptococcus, were identified in 33 of the 35 AIG subjects who underwent culture testing. Researchers reported that AIG subjects were often misdiagnosed as refractory to eradication therapy, probably because achlorhydria in AIG might allow urease-positive bacteria other than H. pylori to colonise the stomach, causing positive 13C-UBT results.
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