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High-frequency quantitative ultrasound for imaging prostate cancer using a novel micro-ultrasound scanner

Ultrasound in Medicine and Biology Apr 10, 2018

Rohrbach D, et al. - In order to support the assumption that quantitative ultrasound (QUS) could provide a more sensitive means of targeting biopsies and directing focal treatments to cancer-suspicious regions in the prostate, researchers used a 29-MHz, transrectal ultrasound (TRUS), micro-ultrasound system and transducer (ExactVu micro-ultrasound, Exact Imaging, Markham, Canada) to acquire radio frequency data from 163 patients immediately before 12-core biopsy procedures, comprising 1,956 cores. In this work, they assessed classifier performance using area-under-the-curve (AUC) values obtained from receiver operating characteristic (ROC) analyses with 10-fold cross-validation. With AUC values of 0.81, they identified the initial results as very encouraging for developing a new, predominantly user-independent, prostate-cancer, risk-assessing tool.
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