Bonnet N, Martin O, Boubaya M, et al. - In severe coronavirus disease 2019 (COVID-19), the preventive effect of high flow nasal canula oxygen therapy (HFNO) against invasive mechanical ventilation (IMV) has not been well established. Researchers here compared two strategies of oxygenation (conventional oxygenation and HFNO) in critically ill COVID 19 patients with respect to the linked risk of IMV. They conducted a bicenter retrospective study including 138 patients. Of these patients, 62 (45%) underwent treatment with standard oxygen therapy (SOT) alone, and 76 (55%) with HFNO. Outcomes revealed a lower rate of invasive mechanical ventilation in correlation with receiving high flow nasal canula oxygen for ARF due to COVID-19.