Goudman L, De Smedt A, Eldabe S, et al. - In this study, the effectiveness of high-dose spinal cord stimulation (HD-SCS) in patients with failed back surgery syndrome (FBSS) was explored. Furthermore, researchers sought to create a prediction model for a holistic responder. They recruited a total of 194 patients to a multicenter real-world registry. They assessed self-reporting outcome variables at baseline (before SCS) and at 1, 3, and 12 months of HD-SCS implant. The data exhibited that in patients with FBSS, clinically significant and sustained pain relief over a period of 12 months was achieved with HD-SCS. The results demonstrated that HD-SCS also achieved an improvement in sleep quality, functionality, and a decrease in pain medication.