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High dose and low dose oxytocin regimens as determinants of successful labor induction: A multicenter comparative study

BMC Pregnancy and Childbirth Apr 26, 2020

Tesemma MG, et al. - The effects of high dose vs low dose oxytocin regimens on success of labor induction were determined. Researchers prospectively conducted a hospital-based comparative cross-sectional study including a total of 216 pregnant women who underwent induction of labor at gestational age of 37 weeks and above in four selected hospitals in Ethiopia from October 1, 2017 to May 30, 2018. Observations revealed no significant association of different oxytocin regimen with success of induction. However, slightly shorter induction to delivery time was reported in significant correlation with receiving high dose oxytocin regimen. Participants who received high dose oxytocin vs low dose oxytocin had the mean “Induction to delivery time” of 5.9 h and 6.3 h, respectively. For successful induction, positive determinants were favourable bishop score, emergency induction, performing artificial rupture of membrane and delivery to non-macrosomic fetuses.

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