Klotz D, Seifert V, Baumgartner J, et al. - In this prospective randomized controlled non‐blinded single‐center pilot trial, researchers estimated the effect of high‐flow nasal cannula (HFNC) therapy on respiratory stability during sedation for upper gastrointestinal tract endoscopy in children. Children were assigned randomly to either provide HFNC (2 L/kg/min) or low‐flow nasal oxygen cannula (LFNC, standard care). Fifty children (mean age, 12.3 ± 3.1 years) were recruited and treated with HFNC (n = 25) or LFNC (n = 25). According to findings, in sedated children undergoing upper gastrointestinal endoscopy, HFNC did not increase respiratory stability as opposed to LFNC.