Chang B, Huang A, Saxena R, et al. - In this retrospective study, researchers sought to describe the histologic features in patients with excessive alcohol use who presented with an abnormal hepatic panel and/or abnormal radiographic imaging and did not meet the clinical diagnosis of alcoholic hepatitis or cirrhosis. They described hepatic histology of 62 and 83 excessive drinkers with normal and abnormal serum aspartate transaminase, respectively. Histological evidence of steatosis was observed in 37% of 62 patients with aspartate aminotransferase ≤ 50 U/L. Excessive drinkers with normal transaminase activity have abnormal hepatic histopathology. Future research is required to establish the diagnostic modalities for detecting such anomalies, as well as to better understand their clinical effects and long-term outcomes.