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Hemodynamics and prognostic impact of concomitant mitral stenosis in patients undergoing surgical or transcatheter aortic valve replacement for aortic stenosis

Circulation Oct 15, 2019

Kato N, Padang R, Pislaru C, et al. - Researchers sought to determine how aortic valve replacement (AVR) affects mitral stenosis hemodynamics and the clinical outcomes of patients with severe aortic stenosis with and without mitral stenosis. They retrospectively reviewed 190 patients with severe aortic stenosis and mitral stenosis (age 76±9 years, 42% men); of these, they matched 184 with 362 with severe aortic stenosis without mitral stenosis. These patients underwent surgical AVR or transcatheter AVR for severe aortic stenosis. Analysis of the outcomes revealed that following AVR, nearly half of patients with severe aortic stenosis and mitral stenosis display improvement in mitral valve area (MVA). Nearly half of patients with severe aortic stenosis and significant mitral stenosis continuously had MVA ≤ 2.0 cm2 (true mitral stenosis), which was associated with poorer survival among patients undergoing AVR for severe aortic stenosis.
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