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Hematological inflammatory markers in patients with pemphigus vulgaris

Dermatology Jan 24, 2021

Lyakhovitsky A, Dascalu J, Drousiotis T, et al. - Researchers intended to determine if there is an association between the neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, platelet-to-neutrophil ratio, mean platelet volume, and disease activity in patients with pemphigus vulgaris. The sample consisted of 56 patients (20 men, 36 women; mean age 54 ± 14 years) diagnosed with pemphigus vulgaris. For this retrospective study, participants were divided into those treated and not treated with rituximab (groups 1 and 2), and into those who did and did not develop relapse (groups 3 and 4). The findings indicate that the neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, platelet-to-neutrophil ratio, and mean platelet volume can be useful markers for treatment response monitoring, while early relapse can also be identified by the neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio.

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