Spierings J, Sloeserwij A, Vianen ME, et al. - Researchers applied the validated EuroQoL 5-dimensions 5-levels questionnaire in an observational cohort of 530 patients with immune mediated inflammatory diseases (IMIDs), including connective tissue diseases (32.6%), uveitis (20.8%), inflammatory arthritis (17.7%), psoriasis (15.5%), vasculitis (6.2%), primary antiphospholipid syndrome (4.2%), and autoinflammatory diseases (2.8%), to evaluate as well as compare health-related quality of life (HR-QoL) in these groups. The overall sample, with 67.5% females, had a mean age of 49 years, and mean disease duration of 31.0 months. Either no anti-inflammatory therapy (31.5%), monotherapy (28.7%), or an integration of anti-inflammatory drugs (39.8%) was used. The mean HR-QoL utility score was 0.75. In multinominal logistic regression analysis, a statistically significant link was evident between a very low HR-QoL (utility score (< 0.70)) and female gender, rheumatological IMID or psoriasis, smoking or having smoked in the past, and current biological disease modifying anti-rheumatic drugs use.