Huang CH, Fu Y, Chi CC, et al. - A substantial connection between androgenetic alopecia (AGA) and moderate impairment of health-related quality of life (HRQOL) and emotions was discovered in this systematic review and meta-analysis, however, no link was observed with depressive symptoms. According to the research, patients with AGA may require psychological and psychosocial care.

• In total, 41 studies were included.

• Participants in the study were 7,995 patients.

• It was noted that the pooled Dermatology Life Quality Index score was 8.16.

• The pooled Hair-Specific Skindex-29 score indicated moderate emotional impairment, with a score of 29.22 in the emotion dimension in the meta-analysis.

• The meta-analysis revealed that the pooled Center for Epidemiologic Studies Depression Scale score of 14.98 did not indicate depression.

• Married or coupled status and receipt of medical treatments had a direct association with HRQOL, whereas higher self-rated hair loss severity, lower visual analog scale score, and higher educational level had an inverse association with HRQOL.