Joundi RA, Rebchuk AD, Field TS, et al. - This study was sought to present outcomes on the EuroQol-5D (EQ-5D) from the ESCAPE (Endovascular Treatment for Small Core and Anterior Circulation Proximal Occlusion With Emphasis on Minimizing CT to Recanalization Times) randomized controlled trial at 90 days after stroke, which reported on patient-reported outcome measures after endovascular thrombectomy (EVT). Quantile regression was applied to assess the relationship between EVT and EQ-5D index scores and logistic regression for the association between EVT and symptom-free status among 90-day survivors for each EQ-5D dimension (self-care, usual activities, mobility, pain/discomfort, and anxiety/depression), evaluating for modification by age or sex and adjusting for baseline factors including stroke severity, affected hemisphere, and receipt of alteplase. Via EVT, age, and sex, the relationship between severe disability at 90 days and EQ-5D was assessed with evaluation for modification. This study’s findings demonstrate that individuals treated with EVT report greatly improved health-related quality of life, with relatively larger impact in older individuals and observed benefit across multiple dimensions.