Rogers AH, et al. - Researchers sought to determine if and how health literacy, pain, and opioid misuse are associated among 445 adults with chronic pain (74.6% female, mean age = 38.45 [11.06] years). Results indicate that health literacy may contribute to current opioid misuse, severity of opioid dependence, pain severity, and pain disability among individuals with chronic pain. The opioid public health crisis could be addressed with interventions targeting health literacy among individuals with chronic illness.