Snauwaert E, Van Biesen W, Raes A, et al. - Researchers undertook this prospective multicentre, non-randomized parallel-arm intervention study to compare pre-dialysis β2-microglobulin (β2M) and protein-bound uraemic toxin (PBUT) levels as well as the percentage of protein binding (%PB) in children on post-dilution haemodiafiltration (HDF) vs conventional high- (hf) or low-flux (lf) haemodialysis over 12 months of treatment. Findings revealed that β2M was successfully reduced by post-HDF but there was no additive impact on PBUT over 12 months of treatment. Experts noted that PBUT elimination was complex and hindered by various factors. These factors might vary between children and adults.