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Growth of hepatocellular adenoma during pregnancy: A prospective study

Journal of Hepatology Sep 28, 2019

Marcia Patricia Gaspersz MP, Klompenhouwer AJ, Broker MEE, et al. - Via a multicentre prospective cohort study in pregnant women with suspected hepatocellular adenoma (HCA, n = 66) < 5cm on imaging, experts evaluated aspects of the growth of HCA < 5cm during pregnancy. Growth of HCA was observed in 13 of the pregnancies with the median increase was 14mm. One female whose HCA grew to > 70mm victoriously underwent transarterial embolization at week 26 of pregnancy to inhibit more growth. The other 50 pregnancies progressed without complications. Thus, this study proposes that an HCA < 5cm endures minimum risk for a pregnant woman and none for the child. As in a quarter of cases, the HCA grew in size during pregnancy, close monitoring with ultrasound-examinations, allowing intervention if required, was proposed. In light of the large proportion of misdiagnosed HCA, LCE-MRI should be done to limit needless anxiety in women with a benign liver lesion.
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