Beauruelle C, et al. - Researchers studied each isolate present in a primary culture of a vaginal swab using a new approach based on Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) locus analysis to ascertain the diversity of Group B Streptococcus (GBS) vaginal carriage populations in pregnant women. They identified 8 out of 10 women to be colonized by a single GBS clone, while two of them were observed to be colonized by two strains, leading to a risk of selection of more virulent and/or resistant clones during antibiotic prophylaxis. This CRISPR analysis allowed separation of isolates belonging to a single capsular type and sequence Type, highlighting the greater discriminating power of this approach.