Hong JY, et al. - Researchers investigated the correlation of the grey–white matter ratio (GWR) assessed via early brain computed tomography (CT) within 2 h after the return of spontaneous circulation (ROSC) following cardiac arrest with neurological outcomes after 6 months in post-cardiac arrest patients treated with targeted temperature management (TTM). They enrolled 512 patients assessing data from the Korean Hypothermia Network prospective registry. In 162 (31.6%) and 350 (68.4%) patients, they observed good (CPC 1–2) and poor (CPC 3–5) neurological outcomes, respectively. Findings revealed no independent predictive value of GWR assessed via early brain CT alone for poor neurologic outcomes. However, when used with repeated CT data, it could be useful.