Kuboi T, et al. - In patients with neonatal hyperbilirubinemia, researchers compared the effectiveness of green light-emitting diode (LED) phototherapy and blue LED phototherapy. They randomly allocated hyperbilirubinemia neonates to a group of green LED or blue LED phototherapy. Both groups had 24 h phototherapy, and before and after 24 h phototherapy, blood was sampled. Enzymatic methods were used to measure total serum bilirubin (TSB), and high-performance liquid chromatography was used to measure bilirubin photoisomers. For this prospective randomized controlled trial, 34 infants (green, n = 16; blue, n = 18) were randomized. There was no significant difference between the groups in reduction of TSB after phototherapy. According to findings, both light sources significantly reduced TSB, indicating clinical efficacy.