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Greater fetal crown-rump length growth with the use of in vitro fertilization or intracytoplasmic sperm injection conceptions after thawed vs fresh blastocyst transfers: Secondary analysis of a prospective cohort study

Fertility and Sterility Jan 28, 2021

Cavoretto PI, Farina A, Girardelli S, et al. - Researchers aimed at comparing first-trimester fetal crown-rump length (CRL) measurements in pregnancies obtained after thawed blastocyst transfer vs fresh blastocyst transfer after in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) via performing a prospective longitudinal cohort study of CRL Z scores with adjustment for major confounders. They recruited a total of 365 IVF/ICSI pregnancies in this study (fresh: 161; thawed: 204). Findings revealed greater CRLs at 6–14 weeks in correlation with thawed blastocyst transfers after IVF/ICSI conceptions relative to fresh, and smaller CRLs in both IVF/ICSI groups than the general population. This effect is especially evident prior to 9 weeks and it may favor birth weight difference of thawed vs fresh BT pregnancies.

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