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Greater expression of postprandial inflammatory genes in humans after intervention with saturated when compared to unsaturated fatty acids

European Journal of Nutrition Nov 07, 2017

Monfort-Pires M, et al. - The postprandial expression of inflammatory genes after 2 distinct high-fat breakfast meals, before and after 1-month dietary interventions was assessed. As per findings, a single saturated fatty acids-enriched meal was able to acutely induce the IL-1β expression and regularly consumed could trigger systemic inflammation, while increased unsaturated fatty acids consumption could attenuate the inflammatory status. Researchers identified the necessity for further investigations to enhance understanding how dietary fatty acids and fiber influence cardiometabolic risk profile by modulating inflammatory gene expression and circulating biomarkers.
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