Zhou TL, et al. - In participants aged 40-75 years from The Maastricht Study, researchers investigated if a cross-sectional association of greater systolic and diastolic blood pressure variability (BPV) with memory function (n=1,804), information processing speed (n=1,793), and executive function (n=1,780) may be possible. They derived a composite BPV-index by standardizing within-visit, 24-hour, and 7-day BPV. Adjusting for age, sex, educational level, 24-hour systolic or diastolic pressure levels, and cardiovascular risk factors, they performed linear regression. The investigators found that greater very short-term to mid-term diastolic and, to a lesser extent, systolic BPV could confer a risk for cognitive deterioration in this population, but this risk factor is modifiable.