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Grass-allergic children frequently show asymptomatic low-level IgE co-sensitization and cross-reactivity to wheat

International Archives of Allergy and Immunology Jun 17, 2018

Nilsson N, et al. - Researchers performed this study in a cohort of pollinosis subjects with no diagnosis of wheat allergy, to determine the level and feature of serological immunoglobulin E (IgE) cross-reactivity between grass pollen and wheat in a cohort of pollinosis subjects with no diagnosis of wheat allergy. In the grass-allergic children, they found a common prevalence of wheat sensitization caused by cross-reactivity and also by sensitization to wheat-specific allergens; this was found to be related to allergy to staple foods other than wheat. A subgroup of pollinosis patients was identified, having simultaneous sensitization to wheat and food allergy not only caused by cross-reactions.
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