Hanna M, Balintescu A, Glassford N, et al. - Given a link between glycemic variability during intensive care unit (ICU) admission and death is suggested by emerging evidence, researchers undertook this retrospective, multicenter cohort study to determine if this link is modified by mean glucose, hypoglycemia occurrence, or premorbid glycemic control. Participants were adult patients from five ICUs in Australia and Sweden with available preadmission glycated hemoglobin A1c and ≥ 3 glucose measurements. Experts computed the glycemic lability index (GLI), a measure of glycemic variability, as well as the time‐weighted average blood glucose from all glucose readings. Findings revealed elevated hospital mortality in relation to a high GLI, regardless of the level of mean glycemia, hypoglycemia occurrence, or premorbid glycemic control, among adult patients admitted to ICU in Sweden and Australia. These data lend support to the evaluation of interventions to attenuate glycemic variability during critical illness.