GlycA, a novel inflammatory marker, is associated with subclinical coronary disease
AIDS Feb 04, 2019
Tibuakuu M, et al. – Researchers examined the associations between GlycA and subclinical coronary plaque among HIV-infected and HIV-uninfected men participating in Multicenter AIDS Cohort Study. In this coss-sectional analysis of 935 men with plasma measurement of GlycA and non-contrast cardiac CT and/or coronary CT angiography, they noted higher GlycA levels among HIV-infected individuals. They also noted a significant association of GlycA with several measures of subclinical coronary atherosclerosis, independent of other cardiovascular disease (CVD) risk factors and inflammatory biomarkers in both HIV-infected and HIV-uninfected individuals. Findings thus suggested a potential role of GlycA in CVD risk stratification among HIV patients.
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