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Glucose variability and the risks of stroke, myocardial infarction, and all- cause mortality in individuals with diabetes: retrospective cohort study

Cardiovascular Diabetology Sep 26, 2020

Lee DY, Han K, Park S, et al. - Researchers explored if variability in long-term fasting plasma glucose can prognosticate the development of stroke, myocardial infarction (MI), and all-cause mortality in patients with diabetes. Researchers conducted a retrospective cohort study applying the data provided by the Korean National Health Insurance Corporation. This study included a sum of 624,237 Koreans ≥ 20 years old with diabetes who underwent health evaluations at least twice from 2005 to 2008 and simultaneously more than once from 2009 to 2010 (baseline) without previous histories of stroke or MI. In this nationwide observational study, it was shown that long-term glucose variability displayed a dose-response relationship with the risk of stroke, MI, and all-cause mortality in diabetes.

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