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GLP-1/glucagon receptor co-agonism for treatment of obesity

Diabetologia - Clinical and Experimental Diabetes and Metabolism Sep 16, 2017

Sánchez-Garrido MA, et al. - In this overview, researchers will target on the discovery and translational relevance of dual agonists that pharmacologically function at the receptors for glucagon and glucagon-like peptide-1. This review demonstrates that novel unimolecular, multifunctional peptides have emerged as one of the most promising medicinal approaches to enhance metabolic efficacy and restore normal body weight.
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