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Glaucoma management in patients with aniridia and Boston type 1 Keratoprosthesis

American Journal of Ophthalmology Dec 06, 2019

Nascimento e Silva R, Shen LQ, Chiou CA, et al. - Researchers conducted this retrospective, interventional comparative case series to evaluate results and glaucoma management in eyes with aniridia following Boston type 1 Keratoprosthesis (KPro) implantation. The sample consisted of patients with aniridia and patients with other preoperative diagnoses (excluding Stevens-Johnson syndrome, mucous membrane pemphigoid, and congenital disorders) who had KPro implantation at Massachusetts Eye and Ear with at least 2 years of follow-up. Findings revealed that the aniridia and comparison groups had comparable preoperative visual acuity (VA, mean ± standard deviation, 1.86 ± 0.52 logMAR) and follow-up time (65.6 ± 26.3 months). Eyes with aniridia had more glaucoma and glaucoma surgery than comparison eyes before KPro implantation. Eyes with aniridia achieved comparable VA as comparison eyes with more than 5 years of mean follow-up time despite a higher glaucoma prevalence. When glaucoma is managed aggressively, Boston KPro provides adequate visual rehabilitation in aniridia.
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