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Gestational dyslipidaemia and adverse birthweight outcomes: A systematic review and meta-analysis

Obesity Reviews Jul 19, 2018

Wang J, et al. - This study examined the association between maternal gestational dyslipidaemia and neonatal health outcomes, namely, birthweight, metabolic factors and inflammatory parameters through a systematic review and meta-analysis. For this investigation, Embase, MEDLINE, PubMed, CINAHL Plus and Cochrane Library were searched systematically up to 1 August 2016 for longitudinal studies that evaluated the relationship of maternal lipid levels during pregnancy with neonatal birthweight, or metabolic and inflammatory parameters up to 3 years old. Researchers reported that maternal high triglycerides and low high-density-lipoprotein cholesterol levels throughout pregnancy were correlated with increased birthweight, higher risk of large for gestational age and macrosomia and lower risk of small-for-gestational age. Thereby suggesting the potential under-recognized adverse effects of intrauterine exposure to maternal dyslipidaemia.
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