Martino B, et al. – The a genetic risk score (uGRS) predictivity was analyzed in 61 Chronic Myeloid Leukemia (CML) patients treated with nilotinib. In these patients, the presence of more than 10 allelic variants associated with insulin secretion, processing, sensitivity, and clearance was predictive of prediabetes/diabetes developing. Moreover, in clinical practice uGRS could help tailor the best tyrosine kinase inhibitor (TKI) therapy.