Kang HG, Park JE, Lee SY, et al. - Researchers examined the link between variants in expression quantitative trait loci (eQTLs) within activating transcription factor 3 (ATF3) binding regions and the prognosis of non-small cell lung cancer (NSCLC) following surgery. Participants included 772 NSCLC cases managed with curative surgery. A total of 104 single nucleotide polymorphisms (SNPs) in eQTLs in the ATF3 binding regions were selected by utilizing a public database, and experts assessed the link of these SNPs with disease-free survival (DFS). Significantly worse DFS was observed in relation to HAX1 rs11265425T>G, while significantly better DFS was evident in relation to ME3 rs10400291C>A. In conclusions, functional polymorphisms in ATF3 binding sites, HAX1 rs11265425T>G and ME3 rs10400291C>A were identified to be related to the clinical results of patients in surgically resected NSCLC.