Metogo JAM, Nana TN, Ngongheh BA, et al. - General anesthesia (GA) was compared with regional (spinal and epidural) anesthesia in terms of their perioperative maternal and fetal outcomes via performing a retrospective cohort study of women who underwent CS indicated for acute fetal distress (AFD). Medical records of 117 pregnant women were enrolled who underwent CS indicated for AFD. Of these pregnant women, 83 (70.9%), 29 (24.8%) and 05 (4.3%) women underwent CS under SA, GA and EA respectively. As per outcomes, CS performed for AFD under GA is associated with fetal morbidity. However, this failed to translate into a difference in perinatal mortality when comparison was performed between GA and RA. This finding does not reduce the role of GA, however, the necessity for specific precautions is emphasized like adequate anticipation for neonatal resuscitation to lower neonatal complications linked with CS performed for AFD under GA.