Dimitriu-Leen AC, et al. - Patients who underwent either incomplete or complete revascularization for ST-elevation myocardial infarction (STEMI) and multi-vessel coronary artery disease (CAD) were assessed herein for gender-specific differences in all-cause mortality. Findings demonstrated that no gender-strategy differences occurred in all-cause mortality within 30 days post-STEMI. Not in women but in men who survived the first 30 days, an independent association of incomplete revascularization with all-cause mortality during 5-years follow-up was evident.

Methods

• Researchers included in this study 375 men and 115 women with a first STEMI and multi-vessel CAD without cardiogenic shock at admission or left main (LM) stenosis.
• They assessed 30-day and 5-year all-cause mortality in patients categorized according to gender and revascularization strategy (incomplete and complete revascularization).

Results

• Findings demonstrated that within the first 30 days, men and women with incomplete revascularization vs men with complete revascularization were associated with higher mortality rates.
• However, researchers found that when corrected for baseline characteristics and angiographic features, there was no independent association of the gender-strategy interaction variable with 30-day mortality post-STEMI.
• Furthermore, they noted that within the survivors of the first 30 days, men with incomplete revascularization (compared to men with complete revascularization) were independently related to all-cause mortality during 5 years follow-up (HR 3.07 [95%CI 1.24;7.61], P=0.016).
• In contrast, data reported no independent association of women with incomplete revascularization with 5-year all-cause mortality (HR 0.60 [95%CI 0.14;2.51], P=0.48).