Alexander T, Victor SM, Jayakumaran B, et al. - In this study, gender-related differences in the clinical characteristics and prognosis of patients with ST elevation myocardial infarction (STEMI) within a system of care were investigated. Researchers performed a multicentre, prospective, observational study of a quality-improvement program analyzing patients with STEMI at four hub-and-spoke clusters in the southern state of Tamil Nadu, India. Between 2012 and 2014, a total of 2,420 patients were included, and the data from all four clusters, pre- and post implementation of integrated STEMI systems, were combined for this analysis, with a 1-year follow-up. Compared with men, women have an unfavourable risk profile and adverse short- and long-term prognosis among patients with STEMI.