Tian J, et al. - In this retrospective study, researchers compared optical coherence tomography (OCT)-detected coronary nonculprit plaque features in women vs men with coronary artery disease (CAD). Overall 103 CAD patients with 187 nonculprit plaques detected after OCT on all 3 coronary arteries were included, with 77 (74.8%) men and 26 (25.2%) women. Compared to males, female patients tended to be significantly older and less likely to be current smokers. The presence of lipid-rich plaque, maximum lipid arc, lipid-core length, lipid index (LI), fibrous cap thickness, and the incidence of thin-cap fibroatheroma was assessed via OCT analysis. Factors associated with a larger LI were sex and current smoker, as revealed in the univariate linear regression model. In multivariate analysis, only use of statin was identified as an independent risk factor for a larger LI. In male patients with CAD, larger lipid cores were seen in coronary nonculprit plaques, vs those of female patients.