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Gender differences in homocysteine concentrations, a population-based cross-sectional study

Nutrition, Metabolism & Cardiovascular Diseases Sep 27, 2018

Cohen E, et al. - Given that high concentrations of homocysteine are a risk factor for atherosclerosis and coronary artery disease, authors evaluated if there are differences in homocysteine plasma concentrations according to gender. Researchers assessed data from 9,237 men and 4,353 women examined at a screening center in Israel between 2000-2014. In men, plasma homocysteine concentrations are higher vs women. In developing atherosclerosis and coronary artery disease, this may be a contributing factor to gender differences. They noted 12.6 to be the average homocysteine concentration in men and and 9.6 μmol/L was the average seen in women. Significantly higher low concentrations of vitamin (B12 <200 pmol/L) and low concentrations of folate (<12 nmol/L) were seen in men vs women 20.4% vs 16.0 % and 18.5% vs 10.8% respectively.

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