Bayram E, Coughlin DG, Banks SJ, et al. - This study was intended to explore sex differences in dementia with Lewy bodies (DLB). Researchers compared core DLB features across 55 women and 156 men with pathologically defined DLB in the National Alzheimer’s Coordinating Center. They further repeated these analyses for 55 women and 55 men matched for age, education, and tau burden. In DLB, sex impacts clinical manifestations of underlying pathologies. Even with comparable underlying Lewy body pathology, it has been reported that women are less likely to manifest major DLB features and may be clinically underdiagnosed. Women died older, had fewer years of education, had higher tau burden, but were less likely to be diagnosed with dementia and clinical DLB. Visual hallucinations continued to be less common in women, and fewer women met clinical DLB criteria in the matched sample.