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Gelatine tannate in the management of acute gastroenteritis in children: A randomised controlled trial

BMJ Open Jun 01, 2018

Kolodziej M, et al. - A randomised, double-blind, placebo-controlled trial was performed to evaluate the efficacy of gelatine tannate (a complex of tannic acid with astringent and anti-inflammatory properties, and a protective gelatine) for the treatment of acute gastroenteritis (AGE) in children. Study participants were children younger than 5 years of age with AGE, defined as a change in stool consistency to a loose or liquid form (according to the Bristol Stool Form Scale or Amsterdam Stool Form Scale) and/or an increase in the frequency of evacuations (≥3 in 24 hours), lasting for no longer than 5 days. It was observed in the findings that gelatine tannate was ineffective as an adjunct to rehydration therapy in children with AGE younger than 5 years of age.
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