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Gastric bypass but not sleeve gastrectomy increases risk of major osteoporotic fracture: french population‐based cohort study

Journal of Bone and Mineral Research Mar 24, 2020

Paccou J, Martignène N, Lespessailles E, et al. - This study was undertaken to evaluate the risk of major osteoporotic fracture (MOF – hip, proximal humerus, wrist and distal forearm, and clinical spine) in bariatric surgery patients versus matched controls. Between 2008 and 2018, records from the French National Inpatient database were applied. Researchers recruited a total of 81,984 individuals (aged 40‐65, with BMI ≥ 40 kg/m²) in the study (40,992 in the bariatric surgery group, and 40,992 matched controls). A Cox regression analysis was performed to evaluate the relationship between the risk of any MOF, and respectively bariatric surgery (yes/no), type of surgical procedure (gastric bypass, gastric banding, vertical banded gastroplasty and sleeve gastrectomy) versus no surgery. The results showed that gastric bypass but not sleeve gastrectomy or the other procedures increased risk of major osteoporotic fractures in patients aged 40‐65.

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