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Gait variability can predict the risk of cognitive decline in cognitively normal older people

Dementia and Geriatric Cognitive Disorders Jul 02, 2018

Byun S, et al. - In this 4-year prospective cohort study, researchers examined the connection of gait speed and gait variability (an index of how much gait parameters, such as step time, fluctuate step-to-step) with the risk of cognitive decline in elderly individuals with normal cognitive function. This study was conducted with 91 community-dwelling cognitively normal elderly individuals with no cerebral ischemic burden or Parkinsonism. It was noted that subjects with slow gait speed showed comparable mild cognitive impairment (MCI) risk to those with mid-to-high speed. In multivariate analysis, however, patients with high gait variability showed an approximate 12-fold higher risk of MCI vs those with mid-to-low variability. In cognitively normal elderly individuals without cerebral ischemic burden or Parkinsonism, gait variability could be a better prognosticator of cognitive decline than gait speed.

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