Di Marco R, Hallemans A, Bellon G, et al. - In people with Dravet syndrome (DS), researchers conducted this cross-sectional multi-center study to quantify gait abnormalities. People with a confirmed DS diagnosis were recruited, and stratified according to knee flexion at initial contact (IC) and range of motion (ROM) during stance (atypical crouch: knee flexion > 20° at IC and knee ROM > 15° during stance; straight: knee flexion < 20° at IC). For this investigation, 71 patients were enlisted and assessed with instrumented gait analysis and 52 (mean age 13.8 ± 7.3) were included in the final analysis. Two gait patterns have been discovered: an atypical crouch gait (34.6%) with increased ankle, knee and hip flexion during stance, and decreased walking speed and stride length not linked to muscle-tendon retractions; and a pattern similar to those of healthy age-matched controls, but still showing decreased walking speed and stride length. There have been no differences between the two groups in clinical or anamnestic data. Kinematics abnormalities can be associated with stabilization issues. These findings can guide measures for rehabilitation and prevention.